Fifty People, One Question won the 13th Annual Webby Award for Best Editing in Online Film & Video — credited to Crush + Lovely / Deltree. The same year Twitter won Breakout of the Year and Jimmy Fallon won Person of the Year.
All four original episodes were also selected as Vimeo Staff Picks, and the series was later shortlisted for the inaugural Vimeo Festival + Awards in 2010, judged by David Lynch, M.I.A., Roman Coppola, and Morgan Spurlock.